Kare D
J Intraven Nurs. 1993 Jan-Feb;16(1):37-43.
Drug-induced low white-blood-cell counts have long impaired our ability to treat patients. Colony-stimulating factors are now available for intravenous or subcutaneous administration. These glycoproteins act on hematopoietic cells by binding to specific cell surface receptors and by stimulating proliferation, differentiation, commitment, and activation of new white blood cells. A brief overview of patient population, indications, actions, and adverse reactions for hospital or home use is presented.
药物引起的白细胞计数降低长期以来一直影响我们治疗患者的能力。目前已有可用于静脉注射或皮下注射的集落刺激因子。这些糖蛋白通过与特定的细胞表面受体结合，并刺激新的白细胞的增殖、分化、定向分化和激活，从而作用于造血细胞。本文简要概述了适用于医院或家庭使用的患者群体、适应症、作用及不良反应。
