Maeda S, Okutani R, Kono K, Fukuda T, Okamoto T, Ochiai N, Matsumoto H
Department of Anesthesiology, Hyogo College of Medicine, Nishinomiya.
Masui. 1993 Feb;42(2):288-91.
Because of its anatomical location, mediastinal tumor is frequently accompanied by airway stenosis and signs indicating compression of the heart and large vessels. For this reason, a patient with this tumor often requires an urgent operation. We recently conducted such an operation on a girl 2 year and 7 month old in whom a giant tumor originating from the posterior mediastinum had caused dyspnea. In this case, anesthesia was induced with ketamine. Intubation was carried out while the girl was semiawake. No muscle relaxants were used, and spontaneous ventilation was partially preserved. During the operation, anesthesia was maintained with oxygen, nitrous-oxide and halothane, without using muscle relaxants. Although intratracheal bleeding, caused by manipulation of the tumor, aggravated the blood gas data, this could be coped with by elevating the oxygen concentration in the inspired gas. During the operation, respiratory control with 10cmH2O PEEP was carried out to cope with atelectasis from lung compression by the tumor. The postoperative course was excellent. From anesthetic management of this case we emphasize the following points: (1) preoperative assessment of the relationship between posture and dyspnea and assessment of the locational relationships of the tumor, heart, vessels and trachea, using CT, ultrasonography, bronchoscopy, etc; (2) utilizing a pulse oximeter, monitoring CO2 in expired gas and monitoring CVP during operation; (3) avoidance of the use of muscle relaxants before the improvement of the symptoms arising from tumor-caused compression; and (4) close respiratory care after operation.
由于纵隔肿瘤的解剖位置,它常伴有气道狭窄以及心脏和大血管受压的体征。因此,患有这种肿瘤的患者常常需要紧急手术。我们最近对一名2岁7个月大的女孩进行了这样一台手术,她患有一个起源于后纵隔的巨大肿瘤,已经导致呼吸困难。在这个病例中,用氯胺酮诱导麻醉。在女孩半清醒状态下进行插管。未使用肌肉松弛剂,部分保留自主通气。手术过程中,用氧气、氧化亚氮和氟烷维持麻醉,未使用肌肉松弛剂。尽管肿瘤操作引起的气管内出血使血气数据恶化,但通过提高吸入气体中的氧浓度可以应对。手术过程中,采用10cmH₂O呼气末正压通气进行呼吸控制,以应对肿瘤压迫肺部导致的肺不张。术后恢复过程良好。从该病例的麻醉管理中,我们强调以下几点:(1)术前评估体位与呼吸困难之间的关系,以及利用CT、超声、支气管镜等评估肿瘤、心脏、血管和气管的位置关系;(2)术中使用脉搏血氧仪、监测呼出气体中的二氧化碳和监测中心静脉压;(3)在由肿瘤压迫引起的症状改善之前避免使用肌肉松弛剂;(4)术后密切进行呼吸护理。