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幽门狭窄:克赖斯特彻奇的经验

Pyloric stenosis: the Christchurch experience.

作者信息

Graham D A, Mogridge N, Abbott G D, Kennedy J C, Kempthore P M, Davidson J R

机构信息

Christchurch Hospital.

出版信息

N Z Med J. 1993 Feb 24;106(950):57-9.

PMID:8437761
Abstract

OBJECT

Evaluation of the performance of a general paediatric unit in diagnosis and treatment of infantile hypertrophic pyloric stenosis, including morbidity and measurable outcomes in relationship to changing management.

METHODS

Retrospective case note audit.

RESULTS

In the 11 year period 1980-91, 103 infants underwent surgical correction of pyloric stenosis, after correction of metabolic disturbance. There was a predominance of males (82.5%), but the incidence of first born infants affected was no greater than the population birth order. While the clinical diagnosis was firm in the majority of infants, over 75% had at least one radiologic imaging procedure. On objective criteria, 80% of patients were less than 5% dehydrated, despite having electrolyte and acid-base derangement. The relatively high incidence of mucosal perforation (31.1%) did not lead to further morbidity. The incidence of postoperative vomiting (19.4%) was significantly less than in previously reported series. There were no deaths, one patient suffered longterm neurologic deficit following profound hypoglycaemia. A change in preoperative management to aggressive rehydration did not reduce morbidity, and was associated with an increased median postoperative stay.

CONCLUSIONS

Pyloric stenosis remains a relatively common surgical problem of infancy. The cornerstone of diagnosis remains a clinical one; however there is a place for radiology. Operative repair is elective, following correction of metabolic derangement. In a general paediatric unit, long term sequelae of initial morbidity are rare.

摘要

目的

评估一家普通儿科病房对婴儿肥厚性幽门狭窄的诊断和治疗效果,包括发病率以及与管理方式变化相关的可测量结果。

方法

回顾性病例记录审核。

结果

在1980年至1991年的11年期间,103例婴儿在纠正代谢紊乱后接受了幽门狭窄的手术矫正。男性占主导(82.5%),但首胎受影响婴儿的发病率并不高于总体出生顺序。虽然大多数婴儿的临床诊断明确,但超过75%的婴儿至少接受了一项放射影像学检查。根据客观标准,80%的患者脱水程度低于5%,尽管存在电解质和酸碱紊乱。黏膜穿孔的发生率相对较高(31.1%),但并未导致进一步的发病情况。术后呕吐的发生率(19.4%)明显低于先前报道的系列。无死亡病例,1例患者在严重低血糖后出现长期神经功能缺损。术前管理改为积极补液并未降低发病率,且与术后中位住院时间延长有关。

结论

幽门狭窄仍然是婴儿期相对常见的外科问题。诊断的基石仍然是临床诊断;然而,放射学也有其作用。在纠正代谢紊乱后,手术修复是选择性的。在普通儿科病房,初始发病的长期后遗症很少见。

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