HIV感染中鼻窦炎的影像学检查

Radiographic imaging of sinusitis in HIV infection.

作者信息

Armstrong M, McArthur J C, Zinreich S J

机构信息

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD.

出版信息

Otolaryngol Head Neck Surg. 1993 Jan;108(1):36-43. doi: 10.1177/019459989310800105.

DOI:10.1177/019459989310800105

PMID:8437872

Abstract

Magnetic resonance images (MRI) of the brain from 75 homosexual men were reviewed to evaluate the frequency and severity of incidental sinus disease associated with human immunodeficiency virus (HIV). All scans had been performed for reasons other than a history of sinus disease. The opacification of each sinus cavity was scored such that 0 = normal, 1 = < 25%, 2 = 25% to 75%, and 3 = > 75% opacification. Subjects were then stratified by clinical status into four groups: HIV-, HIV+ without HIV-related symptoms, AIDS-related complex (ARC), or AIDS. Grade 1 mucosal thickening was present in 52% to 55% of HIV- and HIV+ subjects alike. Moderate disease (grade 2 or 3) was seen in seven of 52 HIV+ subjects, but none of the 23 HIV- controls. The incidence of maxillary sinus thickening was 69% in men with AIDS, compared to 30% in HIV- men (chi 2 = 4.1, p < 0.05). Mean maxillary sinus scores were 1.25 +/- 0.29 in those with AIDS compared to 0.43 +/- 0.15 in HIV- men (f = 5.11, p < 0.05). Our results suggest that maxillary sinus disease is more common and more severe in patients who have AIDS.

摘要

回顾了75名同性恋男性的脑部磁共振成像（MRI），以评估与人类免疫缺陷病毒（HIV）相关的偶发性鼻窦疾病的频率和严重程度。所有扫描均因鼻窦疾病史以外的原因进行。对每个鼻窦腔的混浊程度进行评分，0 =正常，1 = <25%，2 = 25%至75%，3 = >75%混浊。然后根据临床状态将受试者分为四组：HIV阴性、无HIV相关症状的HIV阳性、艾滋病相关综合征（ARC）或艾滋病。1级黏膜增厚在HIV阴性和HIV阳性受试者中均占52%至55%。52名HIV阳性受试者中有7人出现中度疾病（2级或3级），但23名HIV阴性对照者中无人出现。艾滋病男性上颌窦增厚的发生率为69%，而HIV阴性男性为30%（χ2 = 4.1，p < 0.05）。艾滋病患者的平均上颌窦评分为1.25±0.29，而HIV阴性男性为0.43±0.15（F = 5.11，p < 0.05）。我们的结果表明，上颌窦疾病在艾滋病患者中更常见且更严重。