Vilanova Juanola J M, Figueras Aloy J, Molina González J, Botet Mussons F, Jiménez González R
Servicio de Neonatología, Hospital Clínico, Facultad de Medicina, Barcelona.
An Esp Pediatr. 1993 Jan;38(1):43-8.
The aim of this work was to evaluate the influence of bronchopulmonary dysplasia on the neurological outcome of the preterm infant requiring assisted ventilation. Thirty-nine preterm infants requiring ventilation support during 72 hours or more were classified into two groups according to the presence or absence of bronchopulmonary dysplasia (BPD). In the BPD group (n = 11), only the incidence of mild cognitive deficits was significantly higher (36.4 % vs 0 %). Our results suggest that the neurological outcome of the infants with BPD is more closely associated with other neonatal events (intraventricular hemorrhage, periventricular leukomalacia, neonatal seizures, longer ventilation support, maximum serum bilirubin levels, low Apgar score at 10 minutes and poor intake of amino acids) than with the presence of BPD. The data of this study suggest that indomethacin reduces the risk of neurological deficits.
这项工作的目的是评估支气管肺发育不良对需要辅助通气的早产儿神经学预后的影响。39名在72小时或更长时间内需要通气支持的早产儿根据是否存在支气管肺发育不良（BPD）分为两组。在BPD组（n = 11）中，仅轻度认知缺陷的发生率显著更高（36.4%对0%）。我们的结果表明，患有BPD的婴儿的神经学预后与其他新生儿事件（脑室内出血、脑室周围白质软化、新生儿惊厥、更长时间的通气支持、最高血清胆红素水平、10分钟时阿氏评分低和氨基酸摄入不良）的关联比与BPD的存在更为密切。这项研究的数据表明吲哚美辛可降低神经缺陷的风险。
