Johannsson P W, Jay A W, Rowlands S
Can J Physiol Pharmacol. 1977 Feb;55(1):72-6. doi: 10.1139/y77-010.
The velocity of human erythrocytes in flow-through tubes of diameter less than 5 mum is measured as a function of driving pressure. The electrical resistance in the lumen of the tube increases when a cell is present, so a pulse can be generated of length inversely proportional to velocity. In the apparatus described the pulses and driving pressure are fed to a computer which derives the correlation between pressure and velocity. Experiments confirm that the resistance to flow of erythrocytes in a narrow tube is substantially the same as that of the suspending medium. The apparatus is being used to study the effects of changes in erythrocyte deformability on flow.
在直径小于5微米的流通管中，测量人体红细胞的流速与驱动压力的函数关系。当有细胞存在时，管腔内的电阻会增加，因此可以产生长度与速度成反比的脉冲。在所描述的装置中，脉冲和驱动压力被输入到一台计算机中，该计算机得出压力与速度之间的相关性。实验证实，红细胞在细管中的流动阻力与悬浮介质的流动阻力基本相同。该装置正用于研究红细胞变形性变化对流动的影响。
