低血糖作为嗜铬细胞瘤切除术后的一种并发症。
Hypoglycemia as a complication of removal of a pheochromocytoma.
作者信息
Allen C T, Imrie D
出版信息
Can Med Assoc J. 1977 Feb 19;116(4):363-4.
Abstract
In a patient with a solitary pheochromocytoma severe hypoglycemia developed following excision of the tumour. The possible causative mechanism was thought to be a reactive relative increase in insulin production secondary to increased endogenous production of glucose, induced by the large amounts of epinephrine produced by the tumour. Alternatively, epinephrine withdrawal following removal of the tumour under phentolamine infusion may have induced increased insulin production and hence potentiated the development of hypoglycemia. Careful monitoring of the blood glucose concentration during and after the operation is recommended to obviate this potentially fatal complication.
摘要
在一名患有孤立性嗜铬细胞瘤的患者中，肿瘤切除后出现了严重低血糖。可能的致病机制被认为是肿瘤产生的大量肾上腺素诱导内源性葡萄糖生成增加，继而导致胰岛素分泌反应性相对增加。另外，在酚妥拉明输注下切除肿瘤后肾上腺素撤离，可能诱导胰岛素分泌增加，从而加剧了低血糖的发生。建议在手术期间及术后仔细监测血糖浓度，以避免这种潜在的致命并发症。
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本文引用的文献
1
ACTH LEVELS IN PLASMA IN PREOPERATIVE AND SURGICALLY STRESSED PATIENTS.术前及手术应激患者血浆中的促肾上腺皮质激素（ACTH）水平
J Clin Invest. 1962 Aug;41(8):1599-605. doi: 10.1172/JCI104618.
2
CYANOTIC MALFORMATIONS OF THE HEART WITH PHEOCHROMOCYTOMA. A REPORT OF FIVE CASES.伴有嗜铬细胞瘤的心脏青紫型畸形。五例报告。
Circulation. 1964 May;29:750-7. doi: 10.1161/01.cir.29.5.750.
3
Endocrine responses during operative procedures.手术过程中的内分泌反应。
Ann Surg. 1959 Aug;150(2):196-201. doi: 10.1097/00000658-195908000-00003.
4
Pheochromocytoma.
Circulation. 1956 Oct;14(4 Part 1):622-30. doi: 10.1161/01.cir.14.4.622.
5
The effect of epinephrine on immunoreactive insulin levels in man.肾上腺素对人体免疫反应性胰岛素水平的影响。
J Clin Invest. 1966 Feb;45(2):228-36. doi: 10.1172/JCI105335.
6
Postoperative glucose metabolism in diabetic and nondiabetic patients. The response of glucose, insulin, growth hormone, corticosteroids, epinephrine, and unesterified fatty acids to extremity surgery.糖尿病和非糖尿病患者术后的葡萄糖代谢。葡萄糖、胰岛素、生长激素、皮质类固醇、肾上腺素和游离脂肪酸对肢体手术的反应。
Arch Surg. 1972 Nov;105(5):741-5. doi: 10.1001/archsurg.1972.04180110064016.
7
Effects of intravenously administered solutions on electrolytes and energy substrates during surgery.手术期间静脉输注溶液对电解质和能量底物的影响。
Can Anaesth Soc J. 1974 May;21(3):285-93. doi: 10.1007/BF03005733.
8
Current management of pheochromocytoma.嗜铬细胞瘤的当前管理。
Ann Surg. 1974 May;179(5):740-8. doi: 10.1097/00000658-197405000-00029.
9
Role of adrenergic receptors in glucose-induced insulin secretion in man.肾上腺素能受体在人体葡萄糖诱导的胰岛素分泌中的作用。
Lancet. 1969 Aug 9;2(7615):301-2. doi: 10.1016/s0140-6736(69)90059-2.
10
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Lancet. 1967 Mar 4;1(7488):478-81. doi: 10.1016/s0140-6736(67)91097-5.
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