Grab D, Hütter W, Haller T, Sterzik K, Terinde R
Universitäts-Frauenklinik Ulm.
Geburtshilfe Frauenheilkd. 1993 Jan;53(1):42-8. doi: 10.1055/s-2007-1023635.
A 4 MHz continuous-wave Doppler device was used to study uterine and umbilical arterial wave forms in 91 pairs of twins between 18th and 40th week of gestation. Biometry and cord localisation were effected by real-time ultrasound. The results of 182 Doppler flow examinations showed that umbilical flow velocimetry may prove relevant for early identification of twin pregnancies with discordant growth. Depending on the interval between examination and delivery, sensitivity and specificity values between 44% and 66%, and 66% and 73%, respectively, were obtained. A high resistance index in umbilical arteries was indicative of intrauterine growth retardation, at a specificity of 69% and a sensitivity of 44%. For uteroplacental as well as foetoplacental flow velocity waveform assessment, singleton reference values may be used, whereas, by reason of its low sensitivity, Doppler flow velocimetry does not lend itself as a primary diagnostic tool for intrauterine growth retardation. It can signal pathologic blood flow profiles, which are often associated with added risks, such as pregnancy-induced hypertension, foetal acidosis and stillbirth and can contribute to early detection of twin pregnancies that require close clinical and cardiotocographic surveillance.
采用一台4兆赫连续波多普勒设备,对91对妊娠18至40周的双胞胎的子宫和脐动脉波形进行研究。通过实时超声进行生物测量和脐带定位。182次多普勒血流检查结果显示,脐血流测速可能有助于早期识别生长不一致的双胎妊娠。根据检查与分娩之间的间隔时间,分别获得了44%至66%以及66%至73%的敏感性和特异性值。脐动脉高阻力指数提示宫内生长迟缓,特异性为69%,敏感性为44%。对于子宫胎盘以及胎儿胎盘血流速度波形评估,可使用单胎参考值,然而,由于其敏感性较低,多普勒血流测速并不适合作为宫内生长迟缓的主要诊断工具。它可以提示病理性血流情况,这往往与诸如妊娠高血压、胎儿酸中毒和死产等额外风险相关,并有助于早期发现需要密切临床和胎心监护的双胎妊娠。