Swartz C M
Department of Psychiatric Medicine, East Carolina University School of Medicine, Greenville, North Carolina.
Neurol Clin. 1993 Feb;11(1):151-60.
The adverse stresses and injuries associated with epileptic seizures are prevented routinely when programmed, controlled grand mal seizures are administered. According to the described concepts of clinical benefit, symptoms of brain illnesses that are without substantial neuronal deterioration, but that have a sense of neurotransmitter dysregulation, are candidates for mitigation by administration of programmed seizures. Such symptoms include delirium, dementia, neuroleptic malignant syndrome, movement disorder, psychosis, and depression. Prior to recommending cortical excision for management of offtial complex epilepsy, a course of programmed seizures should be considered routinely.
当进行程控的、可控的癫痫大发作时，与癫痫发作相关的不良应激和损伤通常可以得到预防。根据所描述的临床益处概念，对于那些没有实质性神经元退化，但存在神经递质失调感觉的脑部疾病症状，通过进行程控发作有可能得到缓解。此类症状包括谵妄、痴呆、抗精神病药恶性综合征、运动障碍、精神病和抑郁症。在推荐进行皮质切除术治疗局灶性复杂性癫痫之前，通常应考虑进行一个疗程的程控发作。
