• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

神经病理学研究对自闭症理解的贡献。

The contribution of neuropathologic studies to the understanding of autism.

作者信息

Kemper T L, Bauman M L

机构信息

Department of Neurology, Boston City Hospital, Massachusetts.

出版信息

Neurol Clin. 1993 Feb;11(1):175-87.

PMID:8441369
Abstract

A review of the neuropathology of infantile autism shows abnormalities in the limbic forebrain and in cerebellar circuits. The role of the cerebellar lesions in the symptomatology of infantile autism is unknown. The cerebellar findings appear to date from a fetal stage of development with evidence for an ongoing process after birth. The timing of the findings in the limbic system is unknown. A postulated role for these findings in the limbic system in infantile autism is presented.

摘要

对婴儿自闭症神经病理学的综述显示,边缘前脑和小脑回路存在异常。小脑病变在婴儿自闭症症状学中的作用尚不清楚。小脑的这些发现似乎始于胎儿发育阶段,并有证据表明出生后仍在持续发展。边缘系统中这些发现出现的时间尚不清楚。本文提出了这些在边缘系统中的发现对婴儿自闭症的假定作用。

相似文献

1
The contribution of neuropathologic studies to the understanding of autism.神经病理学研究对自闭症理解的贡献。
Neurol Clin. 1993 Feb;11(1):175-87.
2
Neuropathology of infantile autism.
Mol Psychiatry. 2002;7 Suppl 2:S12-3. doi: 10.1038/sj.mp.4001165.
3
Microscopic neuroanatomic abnormalities in autism.自闭症中的微观神经解剖学异常。
Pediatrics. 1991 May;87(5 Pt 2):791-6.
4
Childhood autism: a circuit syndrome?儿童自闭症:一种神经回路综合征?
Neurologist. 2003 Mar;9(2):99-109. doi: 10.1097/01.nrl.0000051441.03160.e0.
5
Neurobiology of autism: neuropathology and neuroimaging studies.自闭症的神经生物学:神经病理学与神经影像学研究
Actas Esp Psiquiatr. 2007 Jul-Aug;35(4):271-6.
6
Neuroanatomic imaging in autism.自闭症的神经解剖学成像
Pediatrics. 1991 May;87(5 Pt 2):781-90.
7
Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism.在孤束核(NTS)内进行抑制可改善自闭症动物模型中因小脑损伤导致的环境探索缺陷。
Behav Brain Res. 2007 Jan 10;176(1):109-20. doi: 10.1016/j.bbr.2006.08.008. Epub 2006 Sep 12.
8
Mapping the brain in autism. A voxel-based MRI study of volumetric differences and intercorrelations in autism.绘制自闭症患者的大脑图谱。一项基于体素的磁共振成像研究,探讨自闭症患者的体积差异和相互关系。
Brain. 2005 Feb;128(Pt 2):268-76. doi: 10.1093/brain/awh332. Epub 2004 Nov 17.
9
Autism and Asperger's disorder: are they movement disorders involving the cerebellum and/or basal ganglia?自闭症与阿斯伯格综合征:它们是涉及小脑和/或基底神经节的运动障碍吗?
Brain Res Bull. 2005 Oct 30;67(4):327-34. doi: 10.1016/j.brainresbull.2005.07.011.
10
The neuropathology of the autism spectrum disorders: what have we learned?
Novartis Found Symp. 2003;251:112-22; discussion 122-8, 281-97.

引用本文的文献

1
The Possible Role of Postnatal Biphasic Dysregulation of IGF-1 Tone in the Etiology of Idiopathic Autism Spectrum Disorder.产后胰岛素样生长因子-1(IGF-1)水平双相失调在特发性自闭症谱系障碍病因学中的可能作用
Int J Mol Sci. 2025 May 8;26(10):4483. doi: 10.3390/ijms26104483.
2
Hippocampal-prefrontal functional neural networks in a rat model of fragile X syndrome are poorly organized with limited resiliency.脆性X综合征大鼠模型中的海马-前额叶功能神经网络组织不良,弹性有限。
Sci Rep. 2025 May 8;15(1):16089. doi: 10.1038/s41598-025-99408-8.
3
Atypical Postural Control Variability and Coordination Persist Into Middle and Older Adulthood in Autism Spectrum Disorder.
非典型姿势控制变异性和协调性在自闭症谱系障碍患者的中年及老年期持续存在。
Autism Res. 2025 Apr;18(4):752-764. doi: 10.1002/aur.70024. Epub 2025 Mar 18.
4
Vestibular Function and Postural Control in Children with Autism Spectrum Disorder.自闭症谱系障碍儿童的前庭功能与姿势控制
J Clin Med. 2024 Sep 9;13(17):5323. doi: 10.3390/jcm13175323.
5
Autism risk gene alters neuronal morphology via caspase-3 activity in mouse hippocampal neurons.自闭症风险基因通过小鼠海马神经元中的半胱天冬酶-3活性改变神经元形态。
Front Cell Neurosci. 2024 May 9;18:1320784. doi: 10.3389/fncel.2024.1320784. eCollection 2024.
6
Neurometabolite differences in Autism as assessed with Magnetic Resonance Spectroscopy: A systematic review and meta-analysis.基于磁共振波谱评估的自闭症神经代谢物差异:系统评价和荟萃分析。
Neurosci Biobehav Rev. 2024 Jul;162:105728. doi: 10.1016/j.neubiorev.2024.105728. Epub 2024 May 23.
7
Insights into the structure and function of the hippocampus: implications for the pathophysiology and treatment of autism spectrum disorder.对海马体结构与功能的洞察:对自闭症谱系障碍病理生理学及治疗的启示
Front Psychiatry. 2024 Apr 23;15:1364858. doi: 10.3389/fpsyt.2024.1364858. eCollection 2024.
8
Neuroanatomy of autism: what is the role of the cerebellum?自闭症的神经解剖学:小脑的作用是什么?
Cereb Cortex. 2024 May 2;34(13):94-103. doi: 10.1093/cercor/bhae050.
9
Contribution of the serotonergic system to developmental brain abnormalities in autism spectrum disorder.5-羟色胺能系统对自闭症谱系障碍发育性脑异常的贡献。
Autism Res. 2024 Jul;17(7):1300-1321. doi: 10.1002/aur.3123. Epub 2024 Mar 18.
10
Expression profiles of the autism-related SHANK proteins in the human brain.自闭症相关 SHANK 蛋白在人脑中的表达谱。
BMC Biol. 2023 Nov 13;21(1):254. doi: 10.1186/s12915-023-01712-0.