Suba I, Halmos T, Kautzky L, Jakab A
Belgyógyászati Osztály, Országos Korányi Tbc és Pulmonológiai Intézet, Budapest.
Orv Hetil. 1993 Feb 20;134(8):395-9.
The occurrence of multi-metabolic syndrome was studied by authors on 31 patients with obesity of android type and hypertension. Plasma glucose and plasma insulin levels were investigated during oral glucose tolerance test, plasma lipid levels were determined, furthermore body mass index and waist/hip ratio were calculated. It was considered that in 65 percent of the cases the presence of multi-metabolic syndrome could have been proved. Dyslipidemia in 22 cases, hyperinsulinemia in 20 cases, deterioration of the carbohydrate metabolism in 14 cases could be demonstrated. The negative correlation between glucose- and insulin-responses to glucose challenge may suggest the presence of insulin resistance. No significant difference was found in metabolic parameters between men and women. The multi-metabolic syndrome is regarded by authors as a process which may lead to both type 2 diabetes mellitus and atherosclerosis. According to their appearance about two third of these patients could be screened. Authors emphasize the great significance of this problem and the importance of early diagnosis and prevention.
作者对31例腹型肥胖和高血压患者的多代谢综合征发生情况进行了研究。在口服葡萄糖耐量试验期间检测了血浆葡萄糖和血浆胰岛素水平，测定了血脂水平，此外还计算了体重指数和腰臀比。据认为，65% 的病例可证实存在多代谢综合征。22例存在血脂异常，20例存在高胰岛素血症，14例存在碳水化合物代谢恶化。葡萄糖激发试验中葡萄糖与胰岛素反应之间的负相关可能提示存在胰岛素抵抗。男性和女性在代谢参数方面未发现显著差异。作者认为多代谢综合征是一个可能导致2型糖尿病和动脉粥样硬化的过程。根据其表现，约三分之二的这些患者可以被筛查出来。作者强调了这个问题的重大意义以及早期诊断和预防的重要性。
