Reduction in primary nonfunction of pancreas islet transplants with antithymocyte globulin agents, deoxyspergualin, and splenectomy.
作者信息
Pittman K, Thomas F, McFadden T, Haisch C, Thomas J
机构信息
Department of Surgery, East Carolina University School of Medicine, Greenville, North Carolina.
出版信息
Transplant Proc. 1993 Feb;25(1 Pt 2):986-7.
PMID:8442292
Abstract
These results suggest that DSG and RATG are an especially favored combination in reducing PNF of discordant pig islet xenografts, probably related to the effect of DSG on the macrophage, humoral antibody, or blockade of NK cell activity. More effective immunosuppression such as demonstrated in this study could well be critical in permitting the application on discordant islet xenografts to human clinical diabetes.
摘要
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