Burgmann H, Winkler S, Uhl F, Feucht M, Hellgren U, Bergqvist Y, Feistauer S, Breyer S, Graninger W
Abteilung für Infektionen und Chemotherapie, Innere Medizin I, Wien.
Wien Klin Wochenschr. 1993;105(2):61-3.
A 39 year-old man with malaria due to Plasmodium falciparum received 3500 mg mefloquine over 3 days, in addition to 3250 mg chloroquine and 175/3500 mg sulfadoxine/pyrimethamine. He developed severe neuropsychiatric symptoms and had to be hospitalized. Treatment with diazepam, haloperidol and thioridazine achieved relief of the severe symptoms after 4 days. The patient was still suffering from discrete neuropsychiatric symptoms 8 months after treatment.
一名39岁的恶性疟原虫疟疾患者,除了接受3250毫克氯喹和175/3500毫克磺胺多辛/乙胺嘧啶治疗外,还在3天内接受了3500毫克甲氟喹治疗。他出现了严重的神经精神症状,不得不住院治疗。使用地西泮、氟哌啶醇和硫利达嗪治疗4天后,严重症状得到缓解。治疗8个月后,患者仍有轻微的神经精神症状。