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新生儿病房支原体感染的前瞻性研究

[A prospective study of mycoplasma infection in a neonatal unit].

作者信息

Petitjean J, Bonnin F, Voirin J, Freymuth F, Laloum D

机构信息

Laboratoire de Virologie, Centre Hospitalier Universitaire, Caen.

出版信息

Ann Pediatr (Paris). 1993 Jan;40(1):5-11.

PMID:8442648
Abstract

Ureaplasma urealyticum and Mycoplasma hominis were recovered from nasopharyngeal aspirates from 25% of 63 infants admitted to a neonatal unit; this proportion is significantly higher than that seen in a control population of maternity ward babies (0%). Birth by cesarean section was associated with a reduced risk of recovery of mycoplasmas. No specific diseases were significantly associated with recovery of mycoplasmas; furthermore, no obstetrical factors were associated with recovery of mycoplasmas from the neonates and no association was found between mycoplasma infection and respiratory distress. However, fetal distress, probably of multifactorial origin, was found in 44% of neonates with positive cultures for Ureaplasma urealyticum; this proportion was significantly elevated as compared with the subgroup of infants negative for U. urealyticum, suggesting that fetal distress may increase the infectivity of this opportunistic organism.

摘要

从一家新生儿病房收治的63名婴儿的鼻咽抽吸物中,25%检测出解脲脲原体和人型支原体;这一比例显著高于产科病房婴儿对照组(0%)。剖宫产与支原体检出风险降低有关。未发现特定疾病与支原体检出有显著关联;此外,未发现产科因素与新生儿支原体检出有关,也未发现支原体感染与呼吸窘迫之间存在关联。然而,在解脲脲原体培养阳性的新生儿中,44%出现胎儿窘迫,可能由多种因素引起;与解脲脲原体阴性的婴儿亚组相比,这一比例显著升高,表明胎儿窘迫可能增加这种机会性病原体的感染性。

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