Sissons H A, Steiner G C, Dorfman H D
Department of Pathology, Hospital for Joint Diseases, New York, NY 10003.
Arch Pathol Lab Med. 1993 Mar;117(3):284-90.
We present 20 examples of fibro-osseous lesions of bone, characterized by the presence of varying numbers of rounded calcified structures (calcified spherules). In the past, such lesions have been regarded as ossifying fibromas or cementifying fibromas, the latter because of their histologic similarity to jaw lesions known by that name. In the present series, six lesions showed, in addition to the calcified spherules, typical histologic features of fibrous dysplasia, while a further seven showed atypical bony structures that also suggest a link with fibrous dysplasia. This study has led us to conclude that these lesions of the extragnathic skeleton, containing rounded calcified spherules, represent a variant of fibrous dysplasia.
我们展示了20例骨纤维-骨病变，其特征为存在数量不等的圆形钙化结构（钙化小球）。过去，此类病变被视为骨化性纤维瘤或牙骨质化纤维瘤，后者是因为其组织学特征与已知的同名颌骨病变相似。在本系列病例中，6例病变除钙化小球外，还具有骨纤维异常增殖症的典型组织学特征，另有7例显示非典型骨结构，这也提示与骨纤维异常增殖症有关。本研究使我们得出结论，这些颌骨外骨骼中含有圆形钙化小球的病变代表了骨纤维异常增殖症的一种变体。
