Uhing M R, Bhat R, Philobos M, Raju T N
Department of Pediatrics, University of Illinois College of Medicine, Chicago.
Am J Perinatol. 1993 Jan;10(1):43-5. doi: 10.1055/s-2007-994699.
Infusing normal saline into the uterine cavity, or amnioinfusion, is used to reduce the risk of meconium aspiration syndrome in babies born to women in whom the pregnancy is complicated by thick, meconium-stained amniotic fluid. In this retrospective review of 436 such pregnancies amnioinfusion was performed in 110. In 18.2% of infants in the amnioinfusion group meconium was found in the trachea compared with 29.1% of infants in the untreated group. In the treated group respiratory distress occurred in 2.7%, and meconium aspiration syndrome in 1.8%, whereas in the untreated group these frequencies were 10.1 and 5.5%, respectively. We conclude that saline amnioinfusion in pregnancies complicated by thick, meconium-stained amniotic fluid reduces the risk of respiratory distress in the newborn.
向子宫腔内输注生理盐水，即羊膜腔灌注，用于降低妊娠合并羊水浓稠、胎粪污染的孕妇所分娩婴儿发生胎粪吸入综合征的风险。在这项对436例此类妊娠的回顾性研究中，110例进行了羊膜腔灌注。羊膜腔灌注组18.2%的婴儿气管内发现有胎粪，而未治疗组为29.1%。治疗组呼吸窘迫发生率为2.7%，胎粪吸入综合征发生率为1.8%，而未治疗组这些发生率分别为10.1%和5.5%。我们得出结论，妊娠合并羊水浓稠、胎粪污染时进行生理盐水羊膜腔灌注可降低新生儿呼吸窘迫的风险。
