Boles D B
Department of Psychology, Rensselaer Polytechnic Institute, Troy, NY 12065.
Brain Cogn. 1993 Mar;21(2):181-91. doi: 10.1006/brcg.1993.1014.
Although classical migraine is known to produce lateralized sensory disturbances (e.g., visual "fortification" structures), its effect on higher order processes is unknown. Here four lateralized visual tasks were repeatedly presented to a single subject (the author) over a 2 1/2-year span, during both classical migraine attacks and headache-free periods. Attacks varied as to inferred hemispheric locus. All four tasks ("words," "typing," "bar graphs," and "locations") produced significant or marginally significant visual field (VF) by condition interactions, results generally consistent with a phasic impairment of function in the migrainous hemisphere. A content analysis of notes made during the attacks suggests that among other symptoms, alphabetic indistinctiveness and spatial disturbances are characteristics of left and right hemisphere attacks, respectively. Aspects of the results argue against any major influence of demand characteristics.
尽管已知典型偏头痛会产生偏侧感觉障碍（例如视觉“堡垒”结构），但其对高级认知过程的影响尚不清楚。在此，在两年半的时间里，针对一名受试者（作者本人）在典型偏头痛发作期间和无头痛期，反复进行了四项偏侧视觉任务。发作时推断的半球位置各不相同。所有四项任务（“单词”“打字”“柱状图”和“位置”）在条件交互作用下均产生了显著或边缘显著的视野（VF）变化，结果总体上与偏头痛发作半球功能的阶段性损害一致。对发作期间所做笔记的内容分析表明，除其他症状外，字母模糊和空间干扰分别是左半球和右半球发作的特征。结果的某些方面表明需求特征没有任何重大影响。
