Inokuchi A, Kimmelman C P, Snow J B
Department of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Eur Arch Otorhinolaryngol. 1993;249(8):473-7. doi: 10.1007/BF00168858.
To elucidate the role of trigeminal input on the olfactory system, field-evoked potentials were measured following electrical stimulation of the nasociliary branch of the trigeminal nerve in the olfactory-related structures in the rat brain. Significant potential changes were recorded in the mediodorsal nucleus of the thalamus and the lateral hypothalamic area. In the mediodorsal nucleus of the thalamus, the neurons responding to olfactory bulb electrical stimulation also responded to trigeminal nerve stimulation. Single neuronal responses of mediodorsal thalamic neurons following odorant stimulation were enhanced by blockade of the trigeminal nerve with procaine. These results suggest that olfactory and trigeminal pathways converge on the same neural elements within the mediodorsal nucleus of the thalamus and that the trigeminal input may modulate olfactory input in this nucleus.
为了阐明三叉神经传入对嗅觉系统的作用，在大鼠脑内与嗅觉相关的结构中，对三叉神经鼻睫状支进行电刺激后，测量了场诱发电位。在丘脑背内侧核和下丘脑外侧区记录到了明显的电位变化。在丘脑背内侧核中，对嗅球电刺激有反应的神经元也对三叉神经刺激有反应。用普鲁卡因阻断三叉神经后，气味刺激下丘脑背内侧核神经元的单神经元反应增强。这些结果表明，嗅觉和三叉神经通路在丘脑背内侧核内汇聚于相同的神经元件，并且三叉神经传入可能在此核中调节嗅觉传入。
