Crowther M A, Ralph E D
Department of Medicine, University of Western Ontario, London, Canada.
Clin Infect Dis. 1993 Feb;16(2):288-9. doi: 10.1093/clind/16.2.288.
An unusual case of menstrual toxic shock syndrome (TSS) is described in which the patient had persistent Staphylococcus aureus bacteremia despite therapy with iv cloxacillin. There was no demonstrable evidence of endocarditis or an abscess as a focus for persisting bacteremia. The strain of S. aureus isolated from the blood and vagina produced toxic shock syndrome toxin 1 (TSST-1) and enterotoxin A. Bacteremia occurs uncommonly in association with TSS; however, aggressive high-dose antistaphylococcal therapy should be instituted for treating this possible complication.
本文描述了一例不寻常的月经性中毒性休克综合征（TSS）病例，尽管患者接受了静脉注射氯唑西林治疗，但仍出现持续性金黄色葡萄球菌菌血症。没有可证明的证据表明存在心内膜炎或脓肿作为持续性菌血症的病灶。从血液和阴道分离出的金黄色葡萄球菌菌株产生了中毒性休克综合征毒素1（TSST-1）和肠毒素A。菌血症与TSS相关的情况并不常见；然而，对于治疗这种可能的并发症，应采取积极的大剂量抗葡萄球菌治疗。
