Meadows S E, Zuckerman J D, Koval K J
Eisenhower Medical Center, Rancho Mirage, California.
Bull Hosp Jt Dis. 1993 Winter;52(2):11-6.
The problem of osteomyelitis has, to date, not been completely resolved. Recent research has provided additional insight into the pathogenesis of bone infection. Advances in pharmacology and in surgical techniques have enhanced our ability to treat such infections. Despite these advances, successful treatment of posttraumatic tibial osteomyelitis depends on adherence to several basic principles: complete debridement of necrotic and infected tissue, obtaining bony stability, the elimination of dead space, and the provision of durable soft tissue coverage. Armed with this new knowledge and surgical ability, treatment results have improved. We do not know, however, whether osteomyelitis can ever be "cured," since infections become manifest many years after injury or treatment.
迄今为止，骨髓炎问题尚未得到彻底解决。最近的研究为骨感染的发病机制提供了更多见解。药理学和外科技术的进步提高了我们治疗此类感染的能力。尽管有这些进展，但创伤后胫骨骨髓炎的成功治疗仍取决于坚持几个基本原则：彻底清除坏死和感染组织、实现骨稳定性、消除死腔以及提供持久的软组织覆盖。有了这些新知识和手术能力，治疗效果有所改善。然而，我们不知道骨髓炎是否能被“治愈”，因为感染在受伤或治疗多年后才会显现出来。
