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透析治疗的选择:心血管检查结果的意义

Options in dialysis therapy: significance of cardiovascular findings.

作者信息

Wizemann V, Timio M, Alpert M A, Kramer W

机构信息

Georg-Haas Dialysis Center, Geissen, Germany.

出版信息

Kidney Int Suppl. 1993 Feb;40:S85-91.

PMID:8445844
Abstract

Most patients receiving renal replacement therapy have cardiovascular disease. The most frequent conditions are left ventricular hypertrophy and coronary artery disease. Hemodialysis is associated with a characteristic spectrum of acute complications (such as hypotension, sudden death) that can be explained by typical dialysis-induced effects on the heart. With continuous ambulatory peritoneal dialysis (CAPD) some of those cardiovascular complications are ameliorated due to slow ultra-filtration and absence of an arteriovenous fistula. It is concluded that CAPD might be the preferable option in patients with cardiovascular disease when hemodialysis can only be performed in a standardized and often aggressive manner. However, achievement of medically-defined goals appears to be more important than technique in dialysis therapy.

摘要

大多数接受肾脏替代治疗的患者患有心血管疾病。最常见的病症是左心室肥厚和冠状动脉疾病。血液透析与一系列典型的急性并发症(如低血压、猝死)相关,这些并发症可由透析对心脏产生的典型影响来解释。对于持续性非卧床腹膜透析(CAPD),由于超滤缓慢且不存在动静脉瘘,一些心血管并发症得到了改善。得出的结论是,当只能以标准化且通常较为激进的方式进行血液透析时,CAPD可能是心血管疾病患者的更优选择。然而,在透析治疗中,实现医学定义的目标似乎比技术更为重要。

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