Eaton R P, Sibbitt W L, Bicknell J M, King M K, Griffey R H, Sibbitt R R
Department of Medicine, University of New Mexico School of Medicine, Albuquerque 87131.
Muscle Nerve. 1993 Mar;16(3):307-11. doi: 10.1002/mus.880160311.
To enable the quantitative assessment of peripheral nerve structure and function, we determined the normal values for sural nerve hydration structure as measured by magnetic resonance proton imaging, and for neurological function with scores for neuropathic symptoms, signs, and nerve conduction properties. Normal human sural nerves contain 24.8 +/- 3.4% water. The structural water content of the nerves did not vary systematically in relation to age, height, gender, sural nerve conduction, neurologic symptoms, or examination deficits. In contrast, the neurological function scores were significantly influenced by age and selectively by height. Both nerve structure and function were stable over a 1-year interval. Measurement of human sural nerve water content in vivo by magnetic resonance proton imaging, and quantitation of the neurological profile of symptoms, signs, and conduction velocity are useful, noninvasive tools for the investigation of diseases in which changes in nerve structure may be related to alterations in nerve function.
为了能够对外周神经结构和功能进行定量评估，我们测定了通过磁共振质子成像测量的腓肠神经水合结构的正常值，以及根据神经病变症状、体征和神经传导特性评分得出的神经功能正常值。正常人类腓肠神经含水量为24.8±3.4%。神经的结构含水量与年龄、身高、性别、腓肠神经传导、神经症状或检查缺陷并无系统性差异。相比之下，神经功能评分受年龄显著影响，并选择性地受身高影响。神经结构和功能在1年的时间间隔内保持稳定。通过磁共振质子成像在体内测量人类腓肠神经含水量，以及对症状、体征和传导速度的神经学特征进行定量分析，是用于研究神经结构变化可能与神经功能改变相关的疾病的有用的非侵入性工具。
