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银屑病:发病率与HL - A抗原频率的相关性。

Psoriasis: case rate--HL-A antigen frequency correlations.

作者信息

Thomas R J

出版信息

Dermatologica. 1977;154(1):24-31.

PMID:844638
Abstract

HL-A antigen B17, associated with a high familial frequency of psoriasis, is significantly correlated (r=0.8242) with psoriasis case rates in several countries but HL-A antigen B13 alone, associated with 'early age onset' cases of psoriasis, is not significantly correlated (r=0.4299) with case rate. A sum of the B13 and B17 antigen frequencies, since either antigen has been associated to psoriasis, is correlated with case rate in the populations surveyed (r=0.7405) and is statistically significant.

摘要

与银屑病家族高发率相关的HL - A抗原B17,在几个国家与银屑病发病率显著相关(r = 0.8242),但单独与银屑病“早发型”病例相关的HL - A抗原B13与发病率无显著相关性(r = 0.4299)。由于这两种抗原都与银屑病有关,B13和B17抗原频率之和与所调查人群的发病率相关(r = 0.7405),且具有统计学意义。

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