雄性激素诱导的大脑性别二态性取决于草甸田鼠的光周期。

Androgenic induction of brain sexual dimorphism depends on photoperiod in meadow voles.

作者信息

Kelly K K

机构信息

Department of Psychology, University of California, Berkeley 94720.

出版信息

Physiol Behav. 1993 Feb;53(2):245-9. doi: 10.1016/0031-9384(93)90200-y.

DOI:10.1016/0031-9384(93)90200-y

PMID:8446686

Abstract

Male meadow voles maintained in a long photoperiod (LP) from birth have heavier brains than do females, but in short photoperiods (SP) this sex dimorphism is absent. Testosterone propionate (TP) administration on the second day of postnatal life produced significant increases in brain weight of LP but not SP females at 35 days of age. Short daylengths reduce the responsiveness of the meadow vole nervous system to the masculinizing effects of perinatal testosterone and may, in part, mediate the seasonally reduced sex difference in brain weight.

摘要

从出生起就处于长光照周期（LP）下饲养的雄性草甸田鼠的大脑比雌性的更重，但在短光照周期（SP）下这种性别差异并不存在。在出生后第二天给予丙酸睾酮（TP），会使35日龄的LP雌性而非SP雌性的脑重显著增加。短日照会降低草甸田鼠神经系统对围产期睾酮雄性化作用的反应性，并且可能在一定程度上介导了季节性的脑重性别差异减小。