Levinson M, Bryce A
Intensive Care Unit, Royal Melbourne Hospital, Victoria, Australia.
Anaesth Intensive Care. 1993 Feb;21(1):85-8. doi: 10.1177/0310057X9302100120.
In this prospective study we aimed to determine whether there is any relationship between enteral feeding, gastric colonisation and diarrhoea in the critically ill patient. Sixty-two critically ill patients from an intensive care unit of a major teaching hospital, who satisfied the usual criteria for enteral feeding, were randomised to receive enteral feeding or not for three days followed by a second randomisation to enterally feed or not for three days. Diarrhoea was recorded and cultures taken of both gastric aspirates and stool. There was no significant difference in the incidence of diarrhoea between the groups. Gastric colonisation was unrelated to feeding practice and to the development of diarrhoea. We conclude that in the critically ill patient, enteral feeding does not cause or promote diarrhoea.
在这项前瞻性研究中，我们旨在确定危重症患者的肠内营养、胃定植与腹泻之间是否存在任何关联。来自一家大型教学医院重症监护病房的62名危重症患者，符合肠内营养的常规标准，被随机分为接受或不接受肠内营养三天，之后再进行一次随机分组，接受或不接受肠内营养三天。记录腹泻情况，并对胃吸出物和粪便进行培养。两组之间腹泻发生率无显著差异。胃定植与喂养方式及腹泻的发生无关。我们得出结论，在危重症患者中，肠内营养不会引起或促进腹泻。
