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乳糖吸收不良的诊断与治疗

[Diagnosis and therapy of lactose malabsorption].

作者信息

Palitzsch D

出版信息

Fortschr Med. 1977 Mar 3;95(9):597-600.

PMID:844787
Abstract

Examinations of faeces (pH, Clinitest and Clinistix) are liable to contribute to the diagnosis of lactose malabsorption. To confirm the diagnosis the test is to be repeated while Lactase 500 is added to the child's milk. The enzyme does not split the lactase into the two monosaccharides, thus eliminating the malabsorption. The new drug Lactase 500 was used as a diagnostic parameter and for the treatment of lactose malabsorption in 20 infants. The effect on both groups was confirmed as mentioned by foreign authors. In addition to a very simple diagnostic method, which can be performed in the practitioner's office, there are two methods of treating lactose malabsorption: 1. feeding milk free of lactose, 2. feeding milk with an addition of Lactase 500. As in an earlier publication we assumed that about 10 per cent of the population suffers from secondary malabsorption of lactose, it seems advisable to check with the help of the described to simple methods all children with chronic diarrhoea.

摘要

粪便检查(pH值、尿糖试纸和尿酮试纸)有助于乳糖吸收不良的诊断。为确诊,需在给患儿的牛奶中添加乳糖酶500的同时重复该检测。该酶不会将乳糖分解为两种单糖,从而消除吸收不良。新药乳糖酶500被用作诊断参数,并用于治疗20名婴儿的乳糖吸收不良。正如国外作者所述,对两组的疗效均得到证实。除了一种非常简单且可在医生办公室进行的诊断方法外,还有两种治疗乳糖吸收不良的方法:1. 喂食无乳糖牛奶,2. 喂食添加了乳糖酶500的牛奶。正如我们在早期出版物中所假设的,约10%的人群患有继发性乳糖吸收不良,因此似乎建议借助上述简单方法对所有慢性腹泻儿童进行检查。

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