Kouach M, Jaquinod M, Belaïche D, Sautière P, van Dorsselaer A, Chevaillier P, Briand G
URA 409 CNRS, Université de Lille II, Institut de Recherches sur le Cancer, France.
Biochim Biophys Acta. 1993 Mar 5;1162(1-2):99-104. doi: 10.1016/0167-4838(93)90134-d.
We have redetermined the primary structure for dog-fish protamine using automated amino-acid sequencing associated to mass spectrometry techniques and report, on the basis of these findings, that the previously published amino-acid sequence is incorrect. The correct protamine sequence is 37 amino acids long and differs from the original published sequence by the C-terminal hexapeptide Arg32-Gly-Arg-Arg-Ser-Arg37.