恶性胸腺瘤接受皮质类固醇治疗后发生诺卡菌病。
Nocardiosis after corticosteroid therapy for malignant thymoma.
作者信息
Borges A A, Krasnow S H, Wadleigh R G, Cohen M H
机构信息
Department of Veterans Affairs, Medical Center, Washington, D.C.
出版信息
Cancer. 1993 Mar 1;71(5):1746-50. doi: 10.1002/1097-0142(19930301)71:5<1746::aid-cncr2820710508>3.0.co;2-8.
BACKGROUND
Nocardia asteroides is an opportunistic infection caused by an aerobic actinomycete, which, in the immunocompromised host, can be associated with severe invasive disease with a predilection for the brain.
METHODS AND RESULTS
The authors describe a 62-year-old man with a malignant thymoma that was clinically responsive to oral prednisone. N. asteroides sepsis subsequently developed, leading to his death.
CONCLUSIONS
Nocardiosis should be considered a potential pathogen in this immunocompromised setting.
背景
星形诺卡菌是由需氧放线菌引起的机会性感染，在免疫功能低下的宿主中，可引发严重的侵袭性疾病，且易侵犯脑部。
方法与结果
作者描述了一名62岁患有恶性胸腺瘤的男性，其对口服泼尼松有临床反应。随后发生了星形诺卡菌败血症，导致其死亡。
结论
在这种免疫功能低下的情况下，应将诺卡菌病视为一种潜在病原体。
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