Smith T C, Proops D W, Pearman K, Hutton P
Department of Anaesthesia and Intensive Care, Queen Elizabeth Hospital, Birmingham, UK.
Clin Otolaryngol Allied Sci. 1993 Feb;18(1):69-71. doi: 10.1111/j.1365-2273.1993.tb00814.x.
A detailed analysis was made of nasal capnograms obtained from sleeping children with differing degrees of sleep-induced respiratory obstruction, the severe form being known as obstructive sleep apnoea. Clinical observations of these children were compared with analyses of nasal capnography data. During periods when the degree of obstruction was consistent throughout the first hour of sleep, the means and coefficients of variation of several parameters, derived from the capnograms were calculated. The coefficients of variation showed a close relationship to the degree of obstruction. In comparison, measures of end-tidal carbon dioxide concentration proved to be a very insensitive index of the degree of obstruction. The conclusion is that the usefulness of nasal capnography in predicting and grading obstruction can easily be extended by the use of statistical measures of dispersion and that this concept warrants further work.
对患有不同程度睡眠诱发呼吸阻塞（严重形式为阻塞性睡眠呼吸暂停）的睡眠儿童的鼻二氧化碳图进行了详细分析。将这些儿童的临床观察结果与鼻二氧化碳图数据的分析结果进行了比较。在睡眠的第一个小时内阻塞程度保持一致的时间段内，计算了从二氧化碳图得出的几个参数的均值和变异系数。变异系数与阻塞程度显示出密切关系。相比之下，呼气末二氧化碳浓度的测量结果被证明是阻塞程度非常不敏感的指标。结论是，通过使用离散度的统计量度，鼻二氧化碳图在预测和分级阻塞方面的有用性可以很容易地扩展，并且这一概念值得进一步研究。
