Lagerholm B, Wennersten G
Acta Derm Venereol. 1979;59(2):153-6.
The present paper reports a study on a case of follicular mucinosis exacerbated by sunlight exposure. Provocation with standardized light testing was carried out on both normally pigmented skin and on areas of hypopigmentation representing a residual state after earlier skin lesions but without any signs of active mucinosis follicularis. Typical clinical and histologically verified lesions were provoked by the light test procedure, best seen in hypopigmented areas but with similar changes in normally pigmented skin. Characteristic findings developed gradually, assuming an appearance identical with that of the observed spontaneously elicited lesions after 3--4 weeks. Treatment with carotenoids periodically over several years has provided a proper light protective effect, as only minimal lesions have been noted during these periods, compared with extensive changes during similar periods without treatment.
本文报道了一例因阳光照射而加重的毛囊黏蛋白病病例研究。对正常色素沉着皮肤以及代表早期皮肤病变后残留状态的色素减退区域进行了标准化光试验激发。在色素减退区域最明显,但正常色素沉着皮肤也有类似变化,光试验程序诱发了典型的临床和组织学证实的病变。特征性表现逐渐发展,3至4周后呈现出与自发诱发病变相同的外观。数年间定期使用类胡萝卜素治疗提供了适当的光保护作用,因为与未治疗的类似时期出现的广泛变化相比,这些时期仅观察到轻微病变。