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No beneficial effects of human growth hormone therapy in normal ovulatory patients with a poor ovarian response to gonadotropins.

作者信息

Levron J, Lewit N, Erlik Y, Itskovitz-Eldor J

机构信息

Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.

出版信息

Gynecol Obstet Invest. 1993;35(2):65-8. doi: 10.1159/000292667.

DOI:10.1159/000292667
PMID:8449446
Abstract

We studied the effects of human growth hormone (hGH) in 7 in vitro fertilization (IVF) patients with normal ovulatory menstrual cycles who showed a low response to ovarian stimulation with follicle-stimulating hormone (FSH) and human menopausal gonadotropin (hMG). Human growth hormone therapy had no significant effect on the number of days of gonadotropic stimulation, on the total amount of hMG administered, on the serum estradiol level on the day of human chorionic gonadotropin injection, or on the IVF outcome. Our preliminary results do not encourage the routine use of hGH to improve IVF outcome in normogonadotropic ovulatory patients who respond poorly to the standard FSH/hMG protocol.

摘要

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引用本文的文献

1
Growth hormone cotreatment with gonadotropins in ovulation induction.在排卵诱导中生长激素与促性腺激素联合治疗。
J Endocrinol Invest. 1996 Dec;19(11):763-79. doi: 10.1007/BF03347881.