Palatsi R, Oikarinen A
Acta Derm Venereol. 1979;59(2):157-60.
Identical twins aged 17 and another pair aged 21 are described. One pair had febrile ulcerative conglobate acne; the other, cystic acne. The location of acne, the type of the lesions and the course of the disease were very similar in the two twins of each pair. The testosterone levels of the 17-year-old pair varied and their acne was in the active stage, while the 21-year-old pair had high testosterone levels and their acne was abating. The 17-year-old pair had negative Mantoux reactions and they reacted negatively to DNCB sensitization. The authors suggest that acne skin may have a certain genetically determined local factor, e.g. hormone receptor, which gives rise to acne in a certain hormonal situation.
本文描述了一对17岁的同卵双胞胎和另一对21岁的同卵双胞胎。其中一对患有发热性溃疡性聚合性痤疮；另一对患有囊性痤疮。每对双胞胎中两人的痤疮发病部位、皮损类型和病程非常相似。17岁那对双胞胎的睾酮水平各异，且他们的痤疮处于活动期，而21岁那对双胞胎的睾酮水平较高，且他们的痤疮正在消退。17岁那对双胞胎的结核菌素试验反应为阴性，对二硝基氯苯致敏也呈阴性反应。作者认为，痤疮皮肤可能存在某种由基因决定的局部因素，例如激素受体，在特定的激素环境下会引发痤疮。
