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用三甲沙林浴后照射紫外线治疗斑块状副银屑病、蕈样肉芽肿和塞扎里综合征。

Treatment of parapsoriasis en plaques, mycosis fungoides, and Sézary's syndrome with trioxsalen baths followed by ultraviolet light.

作者信息

Fischer T, Skogh M

出版信息

Acta Derm Venereol. 1979;59(2):171-3.

PMID:84498
Abstract

Three patients with parapsoriasis en plaques (PEP), fifteen with mycosis fungoides (MF), and one with Sézary's syndrome (SS) were given a bath to which a small amount of trioxsalen solution had been added, and then exposed to ultraviolet (UV) radiation from a bank of dysprosium lamps. Within 2--6 months of this treatment the skin lesions healed completely or almost completely in all 3 patients with PEP, in all 7 with MF stage II and in 4 of 5 with MF stage III. Two patients with MF stages IV--V showed a fair degree of improvement. One with erythrodermic form of MF responded, but poorly. The patient with SS and the one with erythrodermic MF responded with severe phototoxic reactions.

摘要

对3例斑块状副银屑病(PEP)患者、15例蕈样肉芽肿(MF)患者和1例塞扎里综合征(SS)患者进行如下治疗:在浴水中加入少量三甲沙林溶液,然后让患者接受一组镝灯发出的紫外线(UV)照射。在该治疗后的2至6个月内,所有3例PEP患者、所有7例II期MF患者以及5例III期MF患者中的4例,其皮肤病变完全或几乎完全愈合。2例IV - V期MF患者有相当程度的改善。1例红皮病型MF患者有反应,但效果不佳。SS患者和红皮病型MF患者出现严重的光毒性反应。

相似文献

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Treatment of parapsoriasis en plaques, mycosis fungoides, and Sézary's syndrome with trioxsalen baths followed by ultraviolet light.用三甲沙林浴后照射紫外线治疗斑块状副银屑病、蕈样肉芽肿和塞扎里综合征。
Acta Derm Venereol. 1979;59(2):171-3.
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Photochemotherapy for mycosis fungoides: a clinical and histological study.蕈样肉芽肿的光化学疗法:一项临床与组织学研究。
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Photochemotherapy for mycosis fungoides: long-term followup study.蕈样肉芽肿的光化学疗法:长期随访研究
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Photochemotherapy in cutaneous T cell lymphoma and parapsoriasis en plaques. Long-term follow-up in forty-three patients.皮肤T细胞淋巴瘤和斑块状副银屑病的光化学疗法。43例患者的长期随访。
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Photochemotherapy for mycosis fungoides.蕈样肉芽肿的光化学疗法
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Quantitative analysis of lymphoid cells in myocosis fungoides, Sézary's syndrome and parapsoriasis en plaques.蕈样肉芽肿、塞扎里综合征和斑块状副银屑病中淋巴细胞的定量分析。
Arch Dermatol Res. 1979 Feb 23;264(1):17-28. doi: 10.1007/BF00417275.
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13-cis-retinoic acid effective in mycosis fungoides. A report from the Scandinavian Mycosis Fungoides Group.13-顺式维甲酸治疗蕈样肉芽肿有效。斯堪的纳维亚蕈样肉芽肿研究小组的报告。
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A retrospective study of the probability of the evolution of parapsoriasis en plaques into mycosis fungoides.斑块状副银屑病演变为蕈样肉芽肿可能性的回顾性研究。
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