急性白血病患者感染的管理

Section of Infectious Diseases and Microbiology, University of Maryland Cancer Center, Baltimore.

Hematol Oncol Clin North Am. 1993 Feb;7(1):293-315.

Substantial improvements have occurred in the infectious diseases management of patients with acute leukemia. It is now unusual for patients receiving initial induction chemotherapy at a major center to die of infectious complications without receiving an adequate course of antineoplastic treatment. Many patients also receive reinduction chemotherapy with prolonged periods of neutropenia without succumbing to major infectious complications. However, the area of management of infections in patients with acute leukemia has remained a dynamic process, with infection management issues that remain complex and controversial.

急性白血病患者的传染病管理已取得显著改善。如今，在主要中心接受初始诱导化疗的患者，若未接受足够疗程的抗肿瘤治疗而死于感染性并发症的情况已不常见。许多患者还接受了再诱导化疗，伴有长时间的中性粒细胞减少，但并未出现严重的感染性并发症。然而，急性白血病患者感染的管理领域仍然是一个动态的过程，感染管理问题依然复杂且存在争议。