Monma Fumihiko, Katayama Naoyuki
Department of Hematology and Oncology, Mie University Graduate School of Medicine.
Nihon Rinsho. 2009 Oct;67(10):1969-73.
The management of microbial infection is one of the important issues for patients with acute myeloid leukemia (AML). They are considered to be at high risk for infection. They should be provided appropriate antimicrobial agents recommended by the Infectious Diseases Society of America (IDSA). Recently, there have been several significant changes in IDSA guidelines especially in the treatment of invasive fungal infection because of developments in several antifungal agents. This document constitutes the recommendations for the management of infection in patients with AML according to the updated guidelines of the IDSA. Evidence about infection control in AML is not enough in contrast to hematopoietic stem cell transplantation. Further studies are necessary to establish the strategy for microbial infections in AML.
微生物感染的管理是急性髓系白血病（AML）患者的重要问题之一。他们被认为处于感染的高风险中。应给予他们美国感染病学会（IDSA）推荐的适当抗菌药物。最近，由于几种抗真菌药物的发展，IDSA指南有了一些重大变化，特别是在侵袭性真菌感染的治疗方面。本文档根据IDSA的最新指南构成了AML患者感染管理的建议。与造血干细胞移植相比，AML中关于感染控制的证据不足。有必要进行进一步研究以确立AML中微生物感染的应对策略。
