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“洛伊达”法在黄疸新生儿肠道活检中检测肠道乳糖酶的应用。

The application of the "Lojda" method for intestinal lactase in intestinal biopsies from jaundiced newborn infants.

作者信息

Bakken A F

出版信息

Histochemistry. 1977 Mar 4;51(2-3):253-5. doi: 10.1007/BF00567229.

DOI:10.1007/BF00567229
PMID:845064
Abstract

A new use of the histochemical method for intestinal lactase activity is described. Peroral intestinal biopsies from newborn light-treated infants with diarrhoea were investigated for brush-border lactase. The lactase activity found in these infants by the histochemical method correlated well with the infants ability to hydrolyze lactose judged by lactose tolerance test.

摘要

本文描述了组织化学方法在检测肠道乳糖酶活性方面的一种新用途。对患有腹泻的接受光照治疗的新生儿进行经口肠道活检，以检测刷状缘乳糖酶。通过组织化学方法在这些婴儿中发现的乳糖酶活性与通过乳糖耐量试验判断的婴儿水解乳糖的能力密切相关。

相似文献

1
The application of the "Lojda" method for intestinal lactase in intestinal biopsies from jaundiced newborn infants.“洛伊达”法在黄疸新生儿肠道活检中检测肠道乳糖酶的应用。
Histochemistry. 1977 Mar 4;51(2-3):253-5. doi: 10.1007/BF00567229.
2
Temproary intestinal lactase deficiency in light-treated jaundiced infants.
Acta Paediatr Scand. 1977 Jan;66(1):91-6. doi: 10.1111/j.1651-2227.1977.tb07813.x.
3
Effect of jaundice phototherapy on intestinal mucosal bilirubin concentration and lactase activity in the congenitally jaundiced Gunn Rat.黄疸光疗对先天性黄疸Gunn大鼠肠黏膜胆红素浓度和乳糖酶活性的影响。
Pediatr Res. 1981 Apr;15(4 Pt 1):345-8. doi: 10.1203/00006450-198104000-00011.
4
[Diagnosis of intestinal lactase deficiency in children. Histochemical lactase determination in connection with results from the peroral lactose test and evaluation of intestinal mucosal structure].[儿童肠道乳糖酶缺乏症的诊断。组织化学法测定乳糖酶并结合口服乳糖试验结果及肠道黏膜结构评估]
Tidsskr Nor Laegeforen. 1977 Mar 20;97(8):414-6.
5
Letter: Intestinal lactase deficiency as a factor in the diarrhea of light-treated jaundiced infants.
N Engl J Med. 1976 Mar 11;294(11):615. doi: 10.1056/NEJM197603112941122.
6
[Intestinal comparative study of mucosa lactase activity with lactose tolerance test in 119 patients (author's transl)].119例患者乳糖耐量试验与肠黏膜乳糖酶活性的肠道比较研究（作者译）
Biol Gastroenterol (Paris). 1976 Apr-May;9(2):121-8.
7
Correlation of lactase activity, lactose tolerance and milk consumption in different age groups.不同年龄组中乳糖酶活性、乳糖耐受性与牛奶摄入量的相关性。
Am J Clin Nutr. 1975 Jun;28(6):595-600. doi: 10.1093/ajcn/28.6.595.
8
[Comparison of lactose absorption, lactase activity and histological changes in blind biopsies from the small intestine].[小肠盲端活检中乳糖吸收、乳糖酶活性及组织学变化的比较]
Tidsskr Nor Laegeforen. 1977 Mar 20;97(8):388-9.
9
Gut transit time and lactose malabsorption during phototherapy. II. A study using raw milk from the mothers of the infants.光疗期间的肠道转运时间和乳糖吸收不良。II. 一项使用婴儿母亲的生鲜乳的研究。
Acta Paediatr Scand. 1980 Jan;69(1):69-71. doi: 10.1111/j.1651-2227.1980.tb07032.x.
10
Characterization of human intestinal lactase and hetero-beta-galactosidases of infants and adults.婴儿和成人肠道乳糖酶及杂合β-半乳糖苷酶的特性分析
Gastroenterology. 1974 Dec;67(6):1107-13.

本文引用的文献

1
Bilirubin, an uncoupler of oxidative phosphorylation in isolated mitochondria.胆红素，一种分离线粒体中氧化磷酸化的解偶联剂。
Nature. 1956 Dec 15;178(4546):1335-7. doi: 10.1038/1781335a0.
2
Influence of phototherapy on unconjugated bilirubin in duodenal bile of newborn infants with hyperbilirubinemia.
Acta Paediatr Scand. 1972 Nov;61(6):693-6. doi: 10.1111/j.1651-2227.1972.tb15968.x.
3
Indigogenic methods for glycosidases. 3. An improved method with 4-Cl-5-Br-3-indolyl-beta-D-fucoside and its application in studies of enzymes in the intestine, kidney and other tissues.糖苷酶的产靛方法。3. 一种使用4-氯-5-溴-3-吲哚基-β-D-岩藻糖苷的改进方法及其在肠道、肾脏和其他组织中酶研究中的应用。
Histochemie. 1971;25(3):195-207. doi: 10.1007/BF00305938.
4
[Coeliac disease in childhood].[儿童乳糜泻]
Tidsskr Nor Laegeforen. 1974 Feb 28;94(6):368-70.