Hall J W, Grose J H
Division of Otolaryngology, University of North Carolina, Chapel Hill 27599-7070.
J Speech Hear Res. 1993 Feb;36(1):210-7. doi: 10.1044/jshr.3601.210.
This study investigated the masking-level difference (MLD) and auditory brainstem response (ABR) in a group of children with a history of otitis media with effusion (OME) and a control group of children with no known history of ear disease. All children had normal hearing at the time of testing. The main goal of the study was to determine whether there was an association between a reduced MLD in the OME children and an abnormal ABR (in terms of prolonged absolute or interwave intervals, or interaural differences in the ABR waveforms). The results indicated that the group of children having a history of OME had significantly reduced MLDs and had significantly prolonged waves III and V, and I-III and I-V interwave intervals. The correlations between MLD and delays in absolute wave or interwave intervals were not significant. However, some correlations between interaural asymmetries of the interwave intervals and the MLD were significant. The results suggest that the reduction in MLD found in children having a history of OME may be related to abnormal brainstem processing.
本研究调查了一组有中耳积液（OME）病史的儿童和一组无已知耳部疾病史的对照儿童的掩蔽级差（MLD）和听觉脑干反应（ABR）。所有儿童在测试时听力均正常。该研究的主要目的是确定OME儿童中MLD降低与ABR异常（根据绝对或波间间隔延长，或ABR波形的耳间差异）之间是否存在关联。结果表明，有OME病史的儿童组MLD显著降低，且波III和波V以及I-III和I-V波间间隔显著延长。MLD与绝对波或波间间隔延迟之间的相关性不显著。然而，波间间隔的耳间不对称与MLD之间的一些相关性是显著的。结果表明，有OME病史的儿童中发现的MLD降低可能与脑干处理异常有关。
