Schuchardt V
Neurologische Universitätsklinik Heidelberg.
Nervenarzt. 1993 Feb;64(2):91-7.
High-dose intravenous immunoglobulin (IVIG) is effective in myasthenia gravis (MG), Guillain-Barré syndrome (GBS), and chronic inflammatory polyneuropathy (CIDP). The effect is equivalent to plasmapheresis (PE), and in GBS perhaps superior. IVIG may be effective, even if PE or corticosteroids have been ineffective -- and vice versa. IVIG may well become the therapy of first choice in MG, GBS, and CIDP as it is easily administered, there are no serious side-effects and there exists no risk of virus transmission. Future studies will show if a combination of PE and IVIG is superior to either of the two treatment schedules alone.
大剂量静脉注射免疫球蛋白（IVIG）对重症肌无力（MG）、吉兰-巴雷综合征（GBS）和慢性炎症性多发性神经病（CIDP）有效。其效果与血浆置换（PE）相当，在GBS中可能更优。即使PE或皮质类固醇治疗无效，IVIG也可能有效——反之亦然。由于IVIG易于给药，没有严重副作用且不存在病毒传播风险，它很可能会成为MG、GBS和CIDP的首选治疗方法。未来的研究将表明，PE和IVIG联合使用是否优于单独使用这两种治疗方案中的任何一种。
