Mistlberger R E
Department of Psychology, Simon Fraser University, Burnaby, British Columbia, Canada.
Physiol Behav. 1993 Mar;53(3):509-16. doi: 10.1016/0031-9384(93)90145-6.
Wheel-running activity of 31 Syrian hamsters was monitored in constant light (LL), dark (DD), and light-dark (LD) under ad lib and restricted food and water access schedules. Free-running or damped circadian wheel-running rhythms of 26 hamsters in LL were entrained by exposure to the restriction schedule. The phase of entrainment was positive, i.e., wheel running anticipated access time. In LD, activity was nocturnal. When food and water were restricted to midlight, five hamsters showed additional activity in anticipation of access time. Thirty hamsters showed a small advance of the phase of nocturnal activity onset. In subsequent DD, anticipatory activity was revealed (unmasked) in several additional cases, and nocturnal activity shifted and entrained to the access schedule in 19 cases. The properties of food anticipation and entrainment under the three lighting conditions support a model of the hamster circadian system that incorporates separate but strongly coupled food/water- and light-entrainable pacemakers.
在自由采食以及食物和水供应受限的条件下，对31只叙利亚仓鼠的轮转活动在持续光照（LL）、黑暗（DD）和明暗交替（LD）条件下进行了监测。通过暴露于受限时间表，LL条件下26只仓鼠的自由运行或阻尼昼夜节律性轮转活动被同步化。同步化阶段为正，即轮转活动先于进食时间。在LD条件下，活动为夜间活动。当食物和水供应限制在光照中期时，五只仓鼠在预期进食时间前表现出额外活动。30只仓鼠夜间活动开始阶段略有提前。在随后的DD条件下，在另外一些情况下发现了预期活动（被揭示），19只仓鼠的夜间活动发生了转移并与进食时间表同步。三种光照条件下的食物预期和同步化特性支持了仓鼠昼夜节律系统的模型，该模型包含独立但紧密耦合的食物/水和光照可同步化的起搏器。
