Robertson C L
Breast Cancer Detection Centers, St Luke's Regional Medical Center, Boise, ID 83712.
Radiology. 1993 Apr;187(1):75-9. doi: 10.1148/radiology.187.1.8451440.
During 1989 and 1990, 25,788 screening and 1,077 diagnostic breast imaging examinations were performed. Audit was performed in 6-month intervals to allow comparison of performance over time. Sensitivity, positive predictive value, and stage of disease were determined for each radiologist, for patients over and those under 50 years of age, and for patients with and for those without a suspect palpable breast abnormality. In the screening portion of the study, 1,539 of 25,788 (5.9%) patients were asked to return for diagnostic breast imaging, 119 of 188 (63%) cancers were stage 0 or stage 1 disease, and a sensitivity of 91% and a positive predictive value of 11% were found. If patients with a palpable breast abnormality were eliminated, 103 of 138 (75%) patients had disease that was less than stage 2. In the diagnostic portion of the study, 296 of 1,077 (27%) patients were referred for biopsy and 53 of 71 (75%) cancers were stage 0 or stage 1 disease. A sensitivity of 97% and a positive predictive value of 24% were found. If patients with a palpable breast abnormality were eliminated, 51 of 63 (81%) patients had disease that was less than stage 2.
1989年至1990年期间,共进行了25788次乳腺筛查和1077次诊断性乳腺成像检查。每隔6个月进行一次审核,以便比较不同时间的检查表现。针对每位放射科医生、50岁及以上和50岁以下的患者,以及有和没有可触及乳腺异常可疑情况的患者,分别确定了敏感度、阳性预测值和疾病分期。在研究的筛查部分,25788名患者中有1539名(5.9%)被要求返回进行诊断性乳腺成像检查,188例癌症中有119例(63%)为0期或1期疾病,敏感度为91%,阳性预测值为11%。如果排除有可触及乳腺异常的患者,138名患者中有103名(75%)的疾病分期低于2期。在研究的诊断部分,1077名患者中有296名(27%)被转诊进行活检,71例癌症中有53例(75%)为0期或1期疾病。敏感度为97%,阳性预测值为24%。如果排除有可触及乳腺异常的患者,63名患者中有51名(81%)的疾病分期低于2期。