Simpson D, Greenwood J, Jarvie D R, Moore F M
Department of Clinical Biochemistry, Royal Infirmary, Edinburgh.
Scott Med J. 1993 Feb;38(1):20-6. doi: 10.1177/003693309303800108.
The use of a drug screening service has been investigated over a nine month period during which 1500 urine samples from 765 patients were analysed. Preliminary drug screening of urine samples was performed by EMIT immunoassays adapted for use on the Cobas Bio analyser; further identification and confirmation were carried out by Toxi-Lab thin-layer chromatography and capillary gas chromatography. A large number of positive results were obtained for benzodiazepines, cannabinoids, methadone and opiates (mainly dihydrocodeine). Only a limited number of urines gave positive results for amphetamine and related stimulants; cocaine metabolite was rarely detected in samples. The service proved to be of considerable value in the management of drug misusers, and for the identification of new substances taken by the local population.
在九个月的时间里对药物筛查服务的使用情况进行了调查，期间分析了来自765名患者的1500份尿液样本。尿液样本的初步药物筛查通过适用于Cobas Bio分析仪的EMIT免疫测定法进行；进一步的鉴定和确证通过Toxi-Lab薄层色谱法和毛细管气相色谱法进行。苯二氮卓类、大麻素、美沙酮和阿片类药物（主要是二氢可待因）获得了大量阳性结果。只有少数尿液对苯丙胺及相关兴奋剂检测呈阳性；样本中很少检测到可卡因代谢物。该服务在药物滥用者的管理以及当地人群所服用新物质的鉴定方面被证明具有相当大的价值。
