Demitsu T, Ishiharajima S, Miyamoto T, Kosuge A, Usui K, Kano T, Suzuki M, Kitajima Y, Yaoita H
Department of Dermatology, Jichi Medical School, Tochigi, Japan.
Dermatology. 1993;186(3):213-6. doi: 10.1159/000247349.
We report the case of a 51-year-old Japanese man with a unique pustulosis. He had multiple erythematous plaques and numerous pinpoint pustules on the trunk and extremities resembling pustular psoriasis. Histologic features revealed a fully developed intraepidermal abscess filled with neutrophils and disrupted epidermal keratinocytes. Mild leukocytosclastic vasculitis was seen in the underlying dermis. A direct immunofluorescence study revealed IgM, Clq, C3 and fibrinogen deposits in the dermal vessels. The patient had also sternoclavicular hyperostosis. We think that this represents a unique type of pustular vasculitis distinct from pustular psoriasis.
我们报告了一例51岁患有独特脓疱病的日本男性病例。他的躯干和四肢有多个红斑斑块以及无数针尖大小的脓疱，类似脓疱型银屑病。组织学特征显示表皮内有一个完全成熟的充满中性粒细胞的脓肿，表皮角质形成细胞遭到破坏。在其下方的真皮层可见轻度白细胞碎裂性血管炎。直接免疫荧光研究显示真皮血管中有IgM、Clq、C3和纤维蛋白原沉积。该患者还患有胸锁关节骨质增生。我们认为这代表了一种有别于脓疱型银屑病的独特脓疱性血管炎类型。
