Collins D F, McIlroy W E, Brooke J D
School of Human Biology and Biophysics, University of Guelph, Ont., Canada.
Brain Res. 1993 Feb 12;603(1):96-101. doi: 10.1016/0006-8993(93)91303-a.
The research question was, do events arising from rhythmic passive movement of the human leg lead to inhibition of the H reflex pathway in the stationary leg contralateral to that movement? Further, as the angular velocity of the passive movement increases, does the contralateral reflex inhibition also increase? Stable stimulation of the tibial nerve elicited H reflexes in the EMG of soleus. Trials involved the stimulated or the contralateral leg being rotated passively in a pedalling motion, at various velocities. The controls were made with the subjects seated and relaxed. The results showed that reflex magnitudes were significantly depressed when the test limb was passively rotated at 60 rpm. in comparison to the seated control trials. Rotation of the opposite limb depressed reflex magnitudes in the test limb, which was stationary. This contralateral inhibition increased, (mean reflex magnitudes of 62.68%, 41.04%, 16.65% and 9.58% of peak-to-peak Mmax), as the velocity of rotation of the opposite limb increased (10, 30, 60, 90 rpm, respectively) (P < 0.01). The effect of movement velocity was interpreted as the result of altered sensory receptor discharge arising from the passive movement. It is concluded that contralateral sensory activity contributes to the movement-elicited afferent discharge which tunes the spinal somatosensory-motor mechanisms for human locomotion.
研究问题是，人类腿部有节奏的被动运动所引发的事件是否会导致对与该运动相对侧的静止腿部的H反射通路产生抑制？此外，随着被动运动角速度的增加，对侧反射抑制是否也会增加？对胫神经进行稳定刺激，在比目鱼肌肌电图中引出H反射。试验包括在不同速度下，以蹬踏动作被动旋转受刺激的腿部或对侧腿部。对照组是让受试者坐着放松。结果显示，当测试肢体以60转/分钟的速度被动旋转时，反射幅度与坐着的对照试验相比显著降低。对侧肢体的旋转会降低静止测试肢体的反射幅度。随着对侧肢体旋转速度增加（分别为10、30、60、90转/分钟），这种对侧抑制增加（峰峰值Mmax的平均反射幅度分别为62.68%、41.04%、16.65%和9.58%）（P<0.01）。运动速度的影响被解释为被动运动引起的感觉感受器放电改变的结果。得出的结论是，对侧感觉活动有助于运动引发的传入放电，从而调节人类运动的脊髓躯体感觉-运动机制。
