Smith A G, Shuster S, Thody A J, Peberdy M
J Invest Dermatol. 1977 Apr;68(4):169-70. doi: 10.1111/1523-1747.ep12492633.
Plasma immunoreactive beta-melanocyte stimulating hormone (beta-MSH) has been measured in patients taking a progestogen-only oral contraceptive and in patients taking combined estrogen-progestogen therapy, of whom some had chloasma. Plasma levels did not differ significantly from those in a group of age- and sex-matched controls. It is concluded that the pigmentation of chloasma is not due to increased plasma concentrations of immunoreactive beta-MSH.
已对服用单纯孕激素口服避孕药的患者以及接受雌激素 - 孕激素联合治疗的患者（其中一些患有黄褐斑）测量了血浆免疫反应性β - 黑素细胞刺激素（β - MSH）。血浆水平与年龄和性别匹配的对照组相比无显著差异。结论是，黄褐斑的色素沉着并非由于血浆中免疫反应性β - MSH浓度升高所致。
