Schmidt C, Penneys N S, Ziboh V A, Kiem I, Schlossberg J
J Invest Dermatol. 1977 Apr;68(4):206-9. doi: 10.1111/1523-1747.ep12493028.
Using a sensitive new assay, we have measured the cholesteryl ester and cholesterol contents of stratum corneum from callus, normal skin, psoriatic lesions (plantar and nonplantar), and lamellar ichthyotic lesions (plantar and nonplantar). Cholesteryl ester content of normal stratum corneum was significantly higher than that of callus, suggesting that callus was not a suitable control tissue for further biochemical studies involving sterol content of stratum corneum. Both psoriatic and lamellar ichthyotic scale have increased levels of free cholesterol and decreased levels of esterified cholesterol when compared to appropriate controls.
我们使用一种灵敏的新检测方法，测量了来自胼胝、正常皮肤、银屑病皮损（足底和非足底）以及板层状鱼鳞病皮损（足底和非足底）的角质层中的胆固醇酯和胆固醇含量。正常角质层的胆固醇酯含量显著高于胼胝，这表明胼胝并非用于涉及角质层固醇含量的进一步生化研究的合适对照组织。与相应对照相比，银屑病和板层状鱼鳞病鳞屑中的游离胆固醇水平升高，酯化胆固醇水平降低。
