Rubianes E I, Sánchez J L
Department of Dermatology, University of Puerto Rico, School of Medicine, San Juan.
J Dermatol Surg Oncol. 1993 Jan;19(1):14-6. doi: 10.1111/j.1524-4725.1993.tb03324.x.
Tattooing with iron oxide pigment is used to create a permanent line along the eyelid margins and to cause permanent pigmentation of the eyebrows. However inflammatory sequelae can occur.
To present the development and treatment of a granulomatous inflammation as a sequela of iron oxide tattooing in the eyebrows.
A skin biopsy was performed, Histopathologic examination revealed deposits of reddish-brown pigment and a superficial dermal infiltrate consisting of lymphocytes and giant multinucleated cells (Langhan's and foreign body).
A patient developed a granulomatous reaction to iron oxide after undergoing permanent pigmentation of the eyebrows. Treatment with systemic and topical steroids resulted in marked improvement at 6-month follow-up.
This is an unusual complication. A skin test should be performed on any patient who is to undergo tattooing with iron oxide pigment.
使用氧化铁颜料纹身可沿着眼睑边缘形成永久性线条，并使眉毛产生永久性色素沉着。然而，可能会出现炎症后遗症。
介绍一例因氧化铁纹眉导致的肉芽肿性炎症的发生及治疗情况。
进行了皮肤活检，组织病理学检查显示有红棕色色素沉积以及由淋巴细胞和巨大多核细胞（朗汉斯细胞和异物巨细胞）组成的浅表真皮浸润。
一名患者在进行永久性纹眉后对氧化铁产生了肉芽肿反应。全身和局部使用类固醇治疗后，6个月随访时病情有明显改善。
这是一种不寻常的并发症。对于任何接受氧化铁颜料纹身的患者都应进行皮肤试验。
