碳酸酐酶抑制剂。第11部分。杂环磺酰胺与镧系元素的配位化合物是同工酶I和II的有效抑制剂。
Carbonic anhydrase inhibitors. Part 11. Coordination compounds of heterocyclic sulfonamides with lanthanides are potent inhibitors of isozymes I and II.
作者信息
Supuran C T, Manole G, Andruh M
机构信息
University of Bucharest, Department of Chemistry, Roumania.
出版信息
J Inorg Biochem. 1993 Feb 1;49(2):97-103. doi: 10.1016/0162-0134(93)85019-5.
PMID:8455020
Abstract
A number of 22 lanthanide-containing coordination compounds of sulfonamides 2 and 3 were prepared and characterized by elemental analysis and spectroscopic data. The new compounds proved to be highly potent inhibitors of isozymes I and II of carbonic anhydrase.
摘要
制备了22种含镧系元素的磺酰胺2和3的配位化合物，并通过元素分析和光谱数据对其进行了表征。新化合物被证明是碳酸酐酶同工酶I和II的高效抑制剂。
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