Peterson A S, Schubert J J
J Fam Pract. 1977 Mar;4(3):437-41.
The diagnosis, prognosis, and heredity of glomerulonephritis, in 207 members of one family over five generations was determined. No evidence of significant renal insufficiency or renal associated mortality was found. A history of urinary tract infections was obtained from 58 percent of those with hematuria. Several of those with nephritis also had high-frequency hearing losses. Two females with histories of urinary infections had elevated levels of serum creatinine. Many cases will probably be discovered if families are tested when a patient presents with benign recurrent hematuria with or without red blood cell casts. There may not be an obvious history of kidney disease or hematuria. Hereditary nephritis is not always a progressive renal disease.
对一个家族五代中的207名成员的肾小球肾炎的诊断、预后和遗传情况进行了测定。未发现明显肾功能不全或肾脏相关死亡率的证据。58%血尿患者有尿路感染病史。几名肾炎患者也有高频听力损失。两名有尿路感染病史的女性血清肌酐水平升高。如果在患者出现良性复发性血尿伴或不伴红细胞管型时对家族进行检测，可能会发现许多病例。可能没有明显的肾脏疾病或血尿病史。遗传性肾炎并不总是一种进行性肾病。
