Cheng K, Sawamura Y, Yamauchi T, Abe H
Department of Neurosurgery, Hokkaido University School of Medicine, Sapporo, Japan.
Neurosurgery. 1993 Mar;32(3):458-60; discussion 460. doi: 10.1227/00006123-199303000-00020.
A hypothalamic hamartoma is a congenital tumor-like neural malformation. It is usually seen in children and is associated with neuroendocrinological symptoms, seizures, or psychological impairments. An asymptomatic hypothalamic hamartoma in an adult is extremely rare. This report describes an asymptomatic adult with a large hypothalamic hamartoma associated with polydactyly in his feet. Both polydactyly and hamartoma are rare lesions; therefore, this may not be a coincidental presentation. It is thought to have occurred in the embryonic period presumably between 37 and 40 gestational days.
下丘脑错构瘤是一种先天性肿瘤样神经畸形。它通常见于儿童，与神经内分泌症状、癫痫发作或心理障碍有关。成人无症状性下丘脑错构瘤极为罕见。本报告描述了一名无症状成人，其患有巨大下丘脑错构瘤，并伴有足部多指畸形。多指畸形和错构瘤均为罕见病变；因此，这可能并非偶然表现。据推测，其发生于胚胎期，大概在妊娠37至40天之间。
