Testa D, Fetoni V, Soliveri P, Musicco M, Palazzini E, Girotti F
Department of Neurology, National Neurological Institute C. Besta, Milan, Italy.
Neuropsychologia. 1993 Feb;31(2):207-10. doi: 10.1016/0028-3932(93)90048-5.
Nineteen patients with multiple system atrophy (MSA) of striato-nigral degeneration type were tested to examine cognitive and motor performance. Parkinson's disease (PD) patients and healthy subjects served as controls. The MSA and PD patients showed similar cognitive dysfunction and motor impairment, performing poorly in the visuo-spatial organization, the construction tests and motor assessment tests. Movement times were much longer in MSA than PD patients. The association of nigral with putaminal damage may explain the more severe bradykinesia in MSA.
对19例纹状体黑质变性型多系统萎缩（MSA）患者进行了测试，以检查其认知和运动表现。帕金森病（PD）患者和健康受试者作为对照。MSA和PD患者表现出相似的认知功能障碍和运动损害，在视觉空间组织、构建测试和运动评估测试中表现不佳。MSA患者的运动时间比PD患者长得多。黑质与壳核损伤的关联可能解释了MSA中更严重的运动迟缓。
